ncRNA name | PDGF-B siRNA |
ncRNA Category | siRNA |
Disease name | proliferative vitreoretinopathy (PVR) |
Species | Rattus norvegicus |
Tissues/Cell_line | retinas and the proliferative membranes |
Methods | siRNA injection, ELISA, RT-PCR |
Expression pattern | associated |
Functional description | The combinatorial use of UTMD(ultrasound-targeted microbubble destruction) and rAAV2-mediated RNAi targeting TGF-β2 and PDGF-B can serve as a novel approach to attenuate PVR. |
PubMed ID | 22499528 |
Year | 2012 |
Title | A novel approach to attenuate proliferative vitreoretinopathy using ultrasound-targeted microbubble destruction and recombinant adeno-associated virus-mediated RNA interference targeting transforming growth factor-β2 and platelet-derived growth factor-B. |
Drug-related ncRNA | NO |
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